“Not Good Enough”: How One Dad Led the Change in Diabetes Devices through Grassroots Research and Collaboration
April 6, 2017 - In 2002, Bigfoot Biomedical CEO Jeffrey Brewer’s technology career was flourishing, having founded two successful startup dot-coms that later became publicly traded companies. He had just moved his family from Silicon Valley to New York City, and was ready for new challenges. But when his young son received a devastating diagnosis just weeks after the family settled into their new home, Brewer found himself unable to focus on anything else. Stunned by the lack of information, high risk of error and antiquated devices available to help manage his son’s type 1 diabetes, Brewer began laying the groundwork for his most important technology project to date: automated insulin delivery (AID).
New Philanthropic Venture Fund Launches to Invest in Companies Tackling Type 1 Diabetes
January 27, 2017 - The big type 1 diabetes foundation JDRF this week launched a new financial vehicle to more nimbly invest in companies developing medicines or devices for type 1 diabetes. The JDRF T1D Fund, as the vehicle is being called, launches with $42 million and aims to raise $80 million in its first two years...The new fund's already announced its first investment, taking a minority stake in Bigfoot Biomedical, a startup working on an artificial pancreas that links to a patient's smartphone. The device is widely viewed with excitement in the type 1 diabetes community.
Bigfoot Biomedical: Reimagining Diabetes Care with a Novel AP System
October 24, 2016 - Bigfoot has been generating a great deal of interest within the diabetes community of late - and not just because of its unusual name. The company brings together leading players in the "Do-It-Yourself AP System" and "we are not waiting" movements - diabetes community-led efforts that helped jump-start the current trend toward more connected, technology-enabled diabetes care. Its aim is to offer a best-in-class AP that is secure, highly connected, highly automated, and truly patient-, physician-, and payor-friendly.
I Was Hooked Up to Bigfoot’s Artificial Pancreas
August 19, 2016 - I was diagnosed with Type 1 diabetes in 1974, and heard about the possibility of an artificial pancreas two decades later. Recently, I got to wear one from Bigfoot Biomedical.
I heard the term “artificial pancreas” for the first time in 1995 from Dr. Jay Skyler, the noted diabetes researcher who is now a Professor of Medicine, Pediatrics and Psychology at the University of Miami Miller School of Medicine. Dr. Skyler waxed poetic about a mythical system used to keep blood sugars steady...
Bigfoot Begins Artificial Pancreas Trials
August 10, 2016 - Bigfoot Biomedical came on the scene in 2014 determined to change the way companies look at diabetes technology. They’ve moved forward quickly and are now starting their first clinical trial for their “Smartloop” automated insulin delivery system. Stacey talks to Bigfoot Chief Engineer Lane Desborough about what this system is, what the trial is testing, and how you can find out if you’re eligible to enroll.
Bigfoot Recruits for Its First Artificial Pancreas Trial
August 10, 2016 - Bigfoot Biomedical has obtained the FDA’s blessing to conduct a clinically-supervised test of an algorithm designed to translate readings from a Dexcom CGM into insulin-delivery instructions for a pump. On June 29th, the FDA granted Bigfoot an investigational device exemption (IDE), a form of relaxation of certain FDA requirements for premarket clinical trialing, to test the company’s pump-controlling software. Bigfoot will be proceeding with a feasibility study limited to 50 participants and five clinical facilities.
KCGM-TV Nightscout Origins & What's Next at Bigfoot Biomedical
August 4, 2016 - This is Episode 7, Nightscout Origins & What's Next at Bigfoot Biomedical. ...
Bigfoot Biomedical’s Diabetes Management System Going on Trial
August 1, 2016 - Bigfoot Biomedical is a company working on introducing an “artificial pancreas” for Type 1 diabetics who are on insulin therapy. The company has developed its own algorithms that control the delivery of insulin by a pump based on readings from a continuous glucose monitor (CGM). Now these algorithms are about to be tested in a clinical trial thanks to an FDA Investigational Device Exemption and enrollment of initial patients.
Artificial Pancreas Race Includes a Motivated Underdog
July 22, 2016 - The founders and leaders of tiny Bigfoot Biomedical each have at least one family member living with type 1 diabetes. So their motivation in creating the first artificial pancreas may have more of a personal motivation versus say, Medtronic, which recently confirmed it has applied for FDA approval for its version.
The Milpitas, CA, company, founded in 2014, has received FDA approval of an investigational device exemption (IDE) for the first clinical trial of its “smartloop” automated insulin delivery system.
Bigfoot to Kick Off Closed Loop Clinical Trial!
July 21, 2016 - On June 29, the FDA gave Bigfoot the green light to move forward on its Investigational Device Exemption (IDE) submission, allowing the first clinical study for its "smartloop" system to begin. This three-month clinical study will take place at three sites across the U.S., gathering data that will move the needle on getting this ready for FDA submission in 2017 and hopefully commercialization in 2018!
Bigfoot Biomedical starts clinical trial for artificial pancreas
July 21, 2016 - Startup Bigfoot Biomedical has started a clinical trial for its artificial pancreas device in Type 1 diabetes patients. The move comes after Medtronic ($MDT) recently submitted to the FDA for an approval of its own artificial pancreas product.
The devices giant, though, has a reputation for being technologically challenged when it comes to diabetes--so the startup may have room to best it on that front. If the technology becomes accurate enough, it could eliminate both finger-stick testing for blood glucose and insulin injections and replace that with a patch-based device.
Ones to Watch, ten companies we’re keeping an eye on
June 23, 2016 - It’s tough to pick just 10 medtech startups to profile out of the hundreds or thousands dotting the U.S. landscape, but we tried anyway.
It helped that we kept our criteria simple: A relatively new company, with only one or two (or no) financing rounds under their belts. Some are so deeply in stealth mode that they never responded to our enquiries.
More important in our selection process was that the technology being developed sparked our interest. That made it even tougher to winnow the field, as the array of unmet needs being met by ingenious medical devices is truly inspiring.
Closing the Loop, One Bigfoot Step at a Time
April 20, 2016 - We all want to get our hands on the latest and greatest technology in type 1 diabetes, and it appears a closed-loop system is on the horizon. With several players in the race to bring artificial pancreas technology to market, one company to watch is Bigfoot Biomedical.
Bigfoot’s Artificial Pancreas Could Hit the Market by 2018
April 6, 2016 - There are several companies and groups of researchers racing to bring an artificial pancreas to market, be it one that automates insulin delivery or one that does this and provides glucagon, as well. One of the more intriguing entrants into this race is Bigfoot Biomedical...
Bigfoot Biomedical CEO Jeffrey Brewer - Juicebox Podcast
March 1, 2016 - Bigfoot Biomedical is a company dedicated to the development of a closed loop insulin delivery system. Founded and run by the parents and loved ones of people living with type 1 diabetes, Bigfoot has a personal investment in getting to market as soon as possible. Episode 49 is with Jeffrey Brewer, former CEO of the JDRF and current CEO of Bigfoot. The future isn't so far away.
Bigfoot Biomedical CTO Bryan Mazlish
February 9, 2016 - In 2013, Bryan Mazlish created a home-made artificial pancreas system for use by his wife and son, both of whom have type 1 diabetes. Because Mazlish preferred to stay anonymous, a reporter dubbed him “Bigfoot.” In 2015, Mazlish went public and partnered with two others to create Bigfoot Biomedical. Their goal is to bring this technology & other products to market in order to improve the lives of people with T1D. In our Community Connection, Stacey finds out about Hockey Fights T1D, a new JDRF fundraiser in upstate NY sparked by a two year old’s diagnosis.
Making It Simple: Bigfoot's Approach to the Artificial Pancreas
February 2, 2016 - Jeffrey Brewer is no stranger to the diabetes community. Known by many in the diabetes space as the enterprising CEO of JDRF who launched JDRF’s Artificial Pancreas Project in 2005 at the same time that JDRF also created programming to bring adult type 1s back into the fold, Brewer has been a pivotal figure in bringing a sense of modernity and urgency to type 1 diabetes.
Bigfoot's CEO, Jeffrey Brewer, speaking at Health 2.0 WinterTech 2015
January 13, 2016 - In this presentation, "Meeting in the Middle: The Convergence of Life Sciences and Health Tech," Jeffrey Brewer and other presenters discuss how the fields of life science and health technology mutually benefit one other and how they, as innovators, are making health care more accurate, accessible, and affordable. In this clip, Mr. Brewer demos the first prototype of Bigfoot's smartloop™ automated insulin delivery system.
The Innovative Mindset Your Company Can't Afford to Lose
October 13, 2015 - What’s a parent to do when he learns that his child has a chronic disease such as type 1 diabetes? If you are like Lane Desborough, you don’t wait passively for progress, you connect with others who are likeminded—and then you start a company.
Jeffrey Brewer discusses Bigfoot Biomedical’s Automated Insulin Delivery System
October 10, 2015 - Bigfoot Biomedical has developed a fully functioning, automated insulin delivery solution for the treatment of Type 1 Diabetes (T1D). By integrating its FDA-approved insulin pump and the leading continuous glucose monitor (CGM) with a smartphone app and a comprehensive, cloud-based data platform, Bigfoot enables a safer and less costly way to treat the millions of people living with T1D. Founded by proven entrepreneurs with track records of innovation and value creation, Bigfoot is creating a durable business of scale, and meeting an important unmet health need...
Computer Experts Deliver Insulin to Diabetic Kids
June 8, 2015 - Parents developed algorithms to monitor children’s blood sugar, provide insulin.
In the world of diabetes, the Holy Grail is a device that can monitor a person’s blood sugar and deliver insulin as needed—effectively an artificial pancreas.
Bigfoot Biomedical Acquires Asante’s Snap Pump Technology and Signs Deal with Dexcom
June 5, 2015 - Bigfoot Biomedical just announced that it has signed a development agreement with Dexcom to integrate CGM data into its future automated insulin delivery system. This rapid news comes just one week after Bigfoot acquired Asante’s technology . While there aren’t many specifics on what Bigfoot has planned, we believe its automated insulin delivery system may include a Dexcom Gen 5 transmitter sending CGM data (via Bluetooth) to a custom-built controller that fits over the Asante disposable insulin pump body.
Bigfoot Biomedical Raises $3M
May 14, 2015 - Bigfoot Biomedical, which is developing a "bionic pancreas," said it raised $3 million from 8 unnamed investors.
Although it’s in stealth mode, Bigfoot executives have said they’d like to complete product development by 2016. The company’s executives include Bryan Mazlish, Juvenile Diabetes Research Foundation CEO Jeffrey Brewer and Jon Brilliant, the former CFO of Welldoc, according to a regulatory filing.
Bigfoot Biomedical’s artificial pancreas is emerging from hack mode with a $15M Series A in the works
May 13, 2015 - Bigfoot Biomedical, known best for its grassroots approach to building an artificial pancreas for Type 1 diabetes, is emerging from hacker mode and raising some capital. The startup just brought in a $3.5 million bridge convertible note, and is looking to raise between $10 million and $15 million in a Series A this summer.
Meet the Bigfoot Family and Their Homemade Closed Loop System
March 4, 2015 - Yes, Bigfoot does exist in the diabetes community and as you may have heard, he lives with his family in New York.
Our friends at diaTribe recently published a comprehensive interview with the mysterious man who'd long been rumored to have secretly created a homemade artificial pancreas system: D-Dad and husband Bryan Mazlish.
Bigfoot Biomedical Sets its Sights on Simplifying Type 1 Diabetes Management
February 18, 2015 - Three leaders in diabetes have come together to form a new type 1 diabetes technology startup called Bigfoot Biomedical and have soft-launched a teaser webpage at bigfootbiomedical.com: “Many didn't believe Bigfoot could be real. It is. And it's coming.”
Diabetes Patients Are Hacking Their Way Toward a Bionic Pancreas
December 24, 2014 - I continue to obsess with tracking down Bigfoot. Please, I tell an official who claims to know the guy, tell him I will guarantee his confidentiality. Meetings in an underground parking garage are an option. But still the Bigfoot character who had supposedly hacked a fully automated bionic pancreas remains in hiding, refusing to talk to anyone. Others have heard about him, too. “I have heard whispered rumors that such a person exists,” says Amy Tenderich, who runs the prominent Diabetes Mine site. “But nobody will tell us who he is.”
Then, an email appears in my inbox. It contains a phone number to call.